• Gran Hotel Domine, Bilbao: It took a lot of architectural chutzpah to erect a contemporary design hotel right next to Frank Gehry’s iconic Guggenheim Museum, but this place is up to the challenge. It’s a sleek yet comfortable place to stay.
  • Hostal de Los Reyes Católicos, Santiago de Compostela: Created by royal order to welcome pilgrims coming to Santiago, it’s the most history-steeped lodging in town—or maybe in Spain.
  • Hotel María Cristina, San Sebastián: Opulent in ways that only a Belle Époque hotel can be, this landmark hotel takes its name from a Spanish Queen and delivers royally when it comes to luxury and first-class service.
  • Gran Hotel Inglés, Madrid: A total refit has transformed this famous old establishment into one of the capital’s most stylish boutique hotels, set in a narrow Las Letras street across from Hemingway’s favorite sherry bar.
  • Hospedería del Real Monasterio, Guadalupe: Here’s a rare opportunity to lodge inside one of Spain’s most beautiful monasteries in this medieval pilgrimage town. Clanking keys, echoing corridors, and pilgrim-friendly prices make this an atmospheric treat.
  • Casa Fuster, Barcelona: Modernisme’s heyday lives again in this deluxe hotel designed as a private home in 1908 by Lluís Domènech i Montaner. Private balconies in many rooms open onto leafy Passeig de Gràcia.
  • Hostal de la Gavina, Sant Feliu de Guíxols: This oasis amid the bustle of the Costa Brava epitomizes gracious living with a hint of Moorish style.
  • Hotel Marqués de Riscal, Elciego: Rioja wine house Marqués de Riscal hired Frank Gehry to design a “City of Wine” melding production facilities with this striking hotel with a shell of anodized titanium. A kissing cousin to the Guggenheim Bilbao.
  • Las Casas de la Judería, Sevilla: Comprising 27 traditional houses in the old Jewish quarter, linked by a labyrinth of passages, flower-filled patios and underground tunnels, this eccentric hotel is full of history and character. There’s a lovely rooftop pool too. 
  • Parador Casa del Corregidor, Arcos de la Frontera: Once the headquarters of the king’s magistrate, this perfectly located parador in Andalucía has a modern wing hanging over the cliff edge. Its terraces have exhilarating views of the Río Guadelete plain below.

Note: This information was accurate when it was published, but can change without notice. Please be sure to confirm all rates and details directly with the companies in question before planning your trip.