Some artists will always be connected to specific places: Ansel Adams' Yosemite; Monet's gardens at Giverny; Georgia O'Keeffe's New Mexico. O'Keeffe fell in love with the Southwest deserts in the 1930s, and in 1949 she moved from the East Coast to Abiquiu, an hour north of Santa Fe. Her paintings of flowers, skulls, and stark landscapes, simultaneously voluptuous and semi-abstract, made her an international art icon who is now considered the "Mother of American Modernism." This museum, a former Baptist church, holds the largest collection of her works in the world. One of the few museums in town open on Mondays, the interior features stark white walls and paintings displayed in minimalist silver frames O'Keeffe designed herself. Free docent talks are offered daily at 10:30am and 2pm, and audio tours are also available ($5). There's a good film providing an overview of the artist's life, and you can also book guided tours of her historic home and studio in Abiquiu.